FDA Fast Tracks Review of AM-111

More hope on the horizon for those of us suffering from sensorineural hearing loss.  Auris, a Swiss biopharmaceutical company, is developing a promising drug called AM-111.

It’s now in clinical trials and the U.S. Food and Drug Administration has just approved it for a “Fast Track” designation.  That means it will now undergo a speeded up review process.

I will be following this development closely.  More reports to come. Meanwhile, here’s the company’s press release:

Continue reading “FDA Fast Tracks Review of AM-111”

A Breakthrough in Curing Hearing Loss?

Another promising development in research into restoring hearing.

The key to restoring lost hearing is finding a way to re-grow hair cells in the cochlea.  We’re born with about 30,000 of these tiny sound detectors and because of exposure to noise, age and some types of antibiotics they die off.

The good news: researchers around the world are working to develop techniques to regenerate hairs cells.  Now comes word that a team at MIT, Brigham and Women’s Hospital, and Massachusetts Eye and Ear have discovered a combination of drugs that does just that.  At least it works in mice.

The MIT press release and another from Brigham and Women’s Hospital have some of the details about the research that was published in the scientific journal The Cell Reports.

For more on the search for a cure check out my posts on CFG166, research at Sunnybrook in Toronto and the Pasteur Institute in Paris.

 

Great Video Explains Hearing Loss

Do you want to know why you are losing your hearing?   This short video explains clearly and simply what is happens to your auditory system as age, noise and disease take their toll.  Highly recommended.

A couple of notes:  It was produced by Signia (formerly Siemans), a hearing aid maker.  And I have turned on the closed captions.

CGF166 – The Latest News

“There have been a couple patients with hearing improvement, so we are definitely encouraged.” – Dr. Lawrence Lustig

There is no cure for sensorineural hearing loss, the type that most of us with aging ears suffer from.  At least not yet.  But as I’ve written about in earlier posts, a pioneering treatment may be on the way.  It’s called CGF166.  It’s the only gene therapy for hearing loss now undergoing human trials in the U.S. and early reports are promising.  Here’s a progress report. Continue reading “CGF166 – The Latest News”